Individual Cardiac Markers

Troponin I & T

Normal: <0.04 ng/mL (varies by assay)

Gold standard biomarker for myocardial injury. Highly sensitive and specific for detecting cardiac damage. Essential for ACS diagnosis and risk stratification.

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BNP / NT-proBNP

BNP: <100 pg/mL | NT-proBNP: <125 pg/mL

Natriuretic peptides released in response to ventricular stretch. Primary marker for heart failure diagnosis and assessment of fluid overload.

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CK-MB

Normal: <5% of total CK or <25 IU/L

Creatine kinase MB isoenzyme. Traditional cardiac marker, now largely replaced by troponin. Useful for detecting reinfarction and procedural complications.

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Myoglobin

Normal: 20-80 ng/mL

Early marker of muscle injury released within hours of myocardial damage. High sensitivity but low specificity. Useful for early rule-out of MI.

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The clinical content and references are curated and reviewed by myself; however, AI was used to assist in organizing, paraphrasing, and formatting the information presented.