Renal Function Tests

BUN

Normal: 6-24 mg/dL

Blood Urea Nitrogen - waste product from protein metabolism filtered by kidneys. Elevated in renal failure, dehydration, and high protein states.

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Creatinine

Normal: 0.6-1.2 mg/dL

Waste product from muscle metabolism. More specific than BUN for kidney function. Used to calculate eGFR and detect AKI.

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eGFR

Normal: ≥90 mL/min/1.73m²

Estimated Glomerular Filtration Rate - calculated measure of kidney filtration. Best overall indicator of kidney function and CKD staging.

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BUN:Cr Ratio

Normal: 10:1 to 20:1

Helps differentiate prerenal azotemia from intrinsic renal failure. Elevated ratio (>20:1) suggests dehydration or decreased renal perfusion.

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Electrolytes

Sodium (Na+)

Normal: 136-145 mEq/L

Primary extracellular cation regulating fluid balance, osmolality, and neuromuscular function.

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Potassium (K+)

Normal: 3.5-5.0 mEq/L

Critical for cardiac and neuromuscular function. Kidney disease is a major cause of hyperkalemia.

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Chloride (Cl-)

Normal: 96-106 mEq/L

Major extracellular anion that helps maintain acid-base balance, osmolality, and electrical neutrality.

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Bicarbonate (HCO3-)

Normal: 22-28 mEq/L

Key buffer in acid-base balance. Decreased in metabolic acidosis (common in renal failure).

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