Bedside Snapshot

Use It For
Benzodiazepine-refractory status epilepticus (second-line); IV seizure therapy when oral is not possible; neonatal seizures after phenobarbital fails (specialist use)
Adult Dose
  • Status epilepticus: 60 mg/kg IV over 10 min (max 4,500 mg). Differs from FDA label: label is 15 min at no more than 15 mg/mL; trials used 10 min (ESETT) or 5 min
  • Maintenance: 500–1,500 mg IV/PO every 12 hr
Pediatric Dose
Age 2 yr and over: 60 mg/kg IV/IO over 10 min (max 4,500 mg). Age 3 months to under 2 yr: 40 mg/kg IV/IO over 5 min (max 2,500 mg). Under 3 months: specialist use
Onset / Duration
IV: peak at end of infusion; median about 10 min to seizure stop in a small ESETT subset (n=14) / about 12 hr; PO: peak about 1 hr / about 12 hr
Do Not Give / Hold If
Known hypersensitivity to levetiracetam (including anaphylaxis or angioedema). Stop for any rash unless clearly unrelated. Reduce maintenance doses when CrCl is below 80 mL/min/1.73 m²
Watch For
Somnolence and airway loss after benzodiazepines (SpO₂, EtCO₂); agitation, psychosis or suicidal thoughts; rash or fever (SJS/TEN, DRESS); diastolic BP in children under 4 yr
Reversal / Rescue
No antidote: supportive care; hemodialysis removes about 50% in 4 hr. Seizures continue: valproate or fosphenytoin, then a midazolam or propofol infusion
Must Remember
Load fully: 60 mg/kg up to 4,500 mg. Vials hold 500 mg/5 mL: a 4,500 mg load is 45 mL of concentrate (9 vials), diluted before use. Keppra is confused with Keflex.

Indications

Emergency & Prehospital

  • Benzodiazepine-refractory convulsive status epilepticus: the second-line drug, used once an adequate dose of lorazepam, midazolam or diazepam has failed. Levetiracetam, fosphenytoin and valproate perform about the same. Each one stops seizures in about half of patients (ESETT trial; ACEP 2024 Level A) (off-label)

ED / ICU / Transport

  • Seizures when oral therapy is temporarily not feasible: Patients on oral levetiracetam get IV at the same daily dose (labeled use of the injection)
  • Neonatal seizures not controlled by phenobarbital: one of the second-line options in the ILAE 2023 neonatal guideline. With cardiac disease it may be the preferred one (off-label)
  • Seizures after cardiac arrest: The 2025 AHA Guidelines for CPR and ECC, Part 11, recommend treating clinically apparent seizures. The same antiseizure drugs used for other causes may be considered (class 2b). The guideline does not name levetiracetam. Treating EEG-only seizures is reasonable. Get an EEG promptly in patients who do not follow commands or who have myoclonus. Routine prophylaxis, and treating myoclonus with no EEG correlate, are not recommended (off-label)
  • Early seizure prophylaxis after severe traumatic brain injury: per neurosurgical protocol (off-label).

Other Uses

  • Partial-onset (focal) seizures: monotherapy or adjunct, age 1 month and older (labeled)
  • Myoclonic seizures in juvenile myoclonic epilepsy: adjunct, age 12 years and older (labeled)
  • Primary generalized tonic-clonic seizures: adjunct, age 6 years and older with idiopathic generalized epilepsy (labeled)
Wrong first drug for these seizures: Eclampsia calls for magnesium sulfate. Low blood sugar calls for dextrose. In active status epilepticus, levetiracetam is never the first drug. Give a benzodiazepine first.

Dosing & Administration

These house doses follow the ESETT, EcLiPSE and ConSEPT trials and the AES 2016 ladder. For status epilepticus, the FDA label is different.

Available Forms

  • Injection concentrate (Keppra, generics): 100 mg/mL in 5 mL (500 mg) single-dose vials; dilute before use. It is the form you will see most in the ED, ICU and transport.
  • Premixed bags (levetiracetam in sodium chloride): 500 mg/100 mL (5 mg/mL), 1,000 mg/100 mL (10 mg/mL) and 1,500 mg/100 mL (15 mg/mL), single-dose. The label covers patients 16 yr and older only. For weight-based pediatric doses, draw up from the 100 mg/mL vial.
  • Tablets: 250 mg, 500 mg, 750 mg and 1,000 mg (immediate release); Keppra XR is the once-daily version for outpatients.
  • Oral solution: 100 mg/mL, for children and feeding tubes.

Adult Dosing

IndicationDose & RouteRepeat / MaxNotes
Status epilepticus, benzodiazepine-refractory (second-line)
60 mg/kg IV over 10 min
Max 4,500 mg single load
After an adequate benzodiazepine dose. Actual weight; cap reached at 75 kg. Seizing 20 min after the load starts (40 min of seizure): different second-line drug or anesthetic infusion (below).
Maintenance after a load (ICU)
500–1,500 mg IV/PO every 12 hr
Label max 3,000 mg/day; refractory status epilepticus up to 1,500 mg every 8 hr (off-label)
Adjust for renal function.
Partial-onset or generalized tonic-clonic seizures (labeled)
500 mg IV/PO every 12 hr; increase by 500 mg per dose every 2 weeks
Max 1,500 mg every 12 hr (3,000 mg/day)
Target 1,500 mg every 12 hr for myoclonic (labeled from 12 yr) and generalized tonic-clonic seizures.
Replacing oral levetiracetam (NPO)
Same total daily dose and frequency IV
Same daily total; no conversion factor
IV (15-min infusion) and oral doses are bioequivalent. No study experience with IV use longer than 4 days; switch to oral when feasible.

For renal dose reductions and dosing weight, see Special Populations.

Pediatric Dosing

IndicationDose (per kg) & RouteMax Single / Max TotalNotes
Status epilepticus, age 2 yr and older (ESETT regimen)
60 mg/kg IV over 10 min
Max 4,500 mg single load
Similar results in children and adults in ESETT.
Status epilepticus, age 3 months to under 2 yr (house regimen), also acceptable at any age from 3 months
40 mg/kg IV over 5 min
Max 2,500 mg single load (EcLiPSE)
EcLiPSE: 6 months to under 18 yr, IV only. ConSEPT: 3 months to 16 yr, IV or IO over 5 min (cap not stated). As effective as phenytoin, faster to give.
Neonatal seizures not responding to phenobarbital (specialist use)
40 mg/kg IV; a further 20 mg/kg if seizures continue
Total 60 mg/kg
Dose used in NEOLEV2, a first-line trial against phenobarbital (40 mg/kg, escalated to 60 mg/kg). The ILAE 2023 guideline names levetiracetam as a second-line option but gives no dose. Confirm with neonatology or pharmacy.
Maintenance, 1 month to under 6 months
7 mg/kg IV/PO every 12 hr; increase every 2 weeks
Recommended (target) 21 mg/kg every 12 hr (42 mg/kg/day)
Labeled dosing for partial-onset seizures.
Maintenance, 6 months to under 4 yr
10 mg/kg IV/PO every 12 hr; increase after 2 weeks
Recommended (target) 25 mg/kg every 12 hr (50 mg/kg/day)
Watch diastolic BP.
Maintenance, 4 to under 16 yr
10 mg/kg IV/PO every 12 hr; increase every 2 weeks
Target 30 mg/kg every 12 hr (60 mg/kg/day); max 3,000 mg/day
Same regimen for generalized tonic-clonic seizures from 6 yr. From 16 yr, use adult dosing.

Double-check weight-based doses at pediatric weight-based dosing. The label gives no renal dosing for children.

Preparation & Administration

  • Dilution (vials): Use 0.9% sodium chloride, lactated Ringer's or D5W. Adult doses of 500–1,500 mg go in 100 mL. Otherwise keep it at no more than 15 mg/mL. Use within 4 hr at room temperature.
  • Status epilepticus load volume: At the label limit of 15 mg/mL, a 4,500 mg load works out to at least 300 mL. ESETT ran it at 50 mg/mL over 10 min. Protocol and pharmacy set the final concentration and volume.
  • Rate: The house rate is 10 min for age 2 yr and over, adults, or 5 min for age 3 months to under 2 yr. That differs from the FDA label, a 15-minute infusion at no more than 15 mg/mL.
  • Line: Use a peripheral IV (IO was used in the pediatric trials). Run it on a pump.
  • Mixing with other antiseizure drugs: see Interactions & Compatibility.
If seizures continue after the load (third-line):
  • Next, use another second-line drug from the AES 2016 ladder: valproate 40 mg/kg IV (max 3,000 mg; avoid under 2 yr and in liver, mitochondrial or urea-cycle disease) or fosphenytoin 20 mg PE/kg IV (max 1,500 mg PE). Lacosamide is an option too, with less study behind it. This ladder gives no dose for it.
  • Refractory status epilepticus: secure the airway (RSI), then start a continuous midazolam or propofol infusion with continuous EEG.
  • Super-refractory: ketamine, pentobarbital or a phenobarbital infusion, alongside neurocritical care.
  • Not waking up after the convulsions stop? Get an EEG to look for nonconvulsive status epilepticus.

Contraindications & Precautions

Contraindications

  • Hypersensitivity to levetiracetam: Reactions have included anaphylaxis and angioedema. In status epilepticus, reach for fosphenytoin or valproate instead (valproate: not under 2 yr or with liver, mitochondrial or urea-cycle disease).

Precautions

  • Renal impairment and older adults: Clearance falls as creatinine clearance falls. Reduce maintenance doses (see Special Populations).
  • Psychiatric history: The risk of agitation, aggression, depression, psychosis and suicidal thoughts is higher.
  • Children 1 month to under 4 yr: Diastolic BP rose in 17% (vs 2% on placebo). Monitor BP.
  • Pregnancy: Drug levels fall, most of all in the third trimester. Watch seizure control closely.
  • Stopping therapy: Taper gradually. Abrupt withdrawal can trigger seizures and status epilepticus. The exception is a serious reaction that forces a stop.
  • SCN8A epilepsy: Seizures have been reported to get worse.

Hold / Reassess If

  • Any rash: stop at the first sign unless clearly not drug-related; do not restart if SJS/TEN is suspected
  • Facial, lip, tongue or airway swelling, hives or hypotension after a dose: stop permanently and treat as anaphylaxis
  • Fever, lymph node swelling or facial edema with organ involvement: stop and evaluate for DRESS
  • New severe agitation, psychosis or suicidal thoughts: notify the prescriber; dose reduction or a different drug may be needed

Adverse Effects & Toxicity

Common

  • Somnolence: 15% (vs 8% on placebo); about 45% at 4,000 mg/day without titration
  • Asthenia and fatigue: 15% in adults
  • Dizziness: 9%; ataxia and incoordination about 3%
  • Non-psychotic behavioral symptoms: 13% of adults and 38% of children 4–16 yr (irritability, agitation, aggression, anxiety, depression)
  • Children: fatigue, aggression, decreased appetite, irritability

Serious / Life-Threatening

EffectRecognitionManagement
Behavioral change and psychosis
Aggression, depression, paranoia, hallucinations; usually early
Notify the prescriber; reduce or switch; suicide precautions if needed
Anaphylaxis or angioedema
Any dose: hives, facial or airway swelling, hypotension
Stop permanently; treat as anaphylaxis with IM epinephrine
SJS/TEN
Rash with mucosal involvement or sloughing; median onset 14–17 days
Stop; never rechallenge
DRESS (multiorgan hypersensitivity)
Fever, rash, lymph node or facial swelling, eosinophilia, organ injury
Stop if no other cause; can be fatal
Blood dyscrasias
Recurrent infection, fever, bleeding or marked weakness
Check a CBC; significant cytopenia: notify the prescriber, consider another drug, avoid abrupt withdrawal

Postmarketing reports also include hyponatremia, pancreatitis, hepatitis, liver failure and acute kidney injury.

Overdose & Toxicity Management

  • Signs: somnolence, agitation, aggression, depressed level of consciousness, respiratory depression and coma.
  • Management: supportive care of airway, breathing and circulation; contact poison control.
  • Antidote: none exists. Hemodialysis removes about 50% of the drug in 4 hr. Consider it in severe overdose or renal failure.

Monitoring

ParameterWhen / How OftenTarget / Act If
Clinical: seizure activity
Continuously during and after the load
Seizures 20 min after the load started: next agent (third-line steps above)
Clinical: mental status and EEG
After convulsions stop
Not improving: continuous EEG to rule out nonconvulsive status epilepticus
Clinical: airway, RR, SpO₂, EtCO₂
Continuously after benzodiazepines plus the load
Falling SpO₂ or rising EtCO₂: support ventilation; prepare to intubate
Clinical: behavior and mood
Every shift after starting or increasing the dose
New aggression, psychosis or suicidal thoughts: notify the prescriber
Clinical: skin
Daily for the first months
Any rash: stop unless clearly unrelated; fever with rash: evaluate for DRESS
Clinical: diastolic BP (age 1 month to under 4 yr)
With routine vital signs
Sustained rise: notify the prescriber
Laboratory: renal function
Baseline and daily in ICU (creatinine, eGFR)
CrCl below 80 mL/min/1.73 m², AKI or new dialysis: reduce maintenance doses
Laboratory: CBC
With weakness, fever, recurrent infection or bleeding
Significant cytopenia (agranulocytosis, pancytopenia, thrombocytopenia): notify the prescriber; consider another drug; avoid abrupt withdrawal
Laboratory: sodium
With confusion, new seizures or lethargy
Low sodium: evaluate; hyponatremia has been reported

Interactions & Compatibility

Clinically Significant Interactions

Drug / ClassEffectWhat To Do
CNS depressants (benzodiazepines, opioids, alcohol, sedatives)
Additive somnolence and respiratory depression
Monitor airway, SpO₂ and EtCO₂, especially right after status epilepticus treatment
Enzyme-inducing antiseizure drugs (carbamazepine, phenytoin)
About 22% faster levetiracetam clearance in children
No dose change recommended
Phenytoin, valproate, warfarin, digoxin, oral contraceptives
No pharmacokinetic interaction in label studies; prothrombin time unchanged
No adjustment; levetiracetam is a good choice with complex drug lists
Probenecid
Raises the inactive metabolite; parent drug unchanged
No adjustment

Levetiracetam skips CYP450 metabolism and binds less than 10% to protein. That keeps it clear of the enzyme and binding interactions that phenytoin and valproate bring.

IV Compatibility

  • Diluents: 0.9% sodium chloride, lactated Ringer's, D5W.
  • Admixture: compatible with lorazepam, diazepam and valproate sodium (label); no data for other antiseizure drugs.
  • Verify with an institutional compatibility resource.

Special Populations

  • Pediatrics: labeled from 1 month of age. Behavioral effects come up more often than in adults. Psychotic symptoms hit 17% of children under 4 yr (vs 5% on placebo). Find the doses in the Pediatric Dosing table.
  • Neonates: phenobarbital stays first-line under the ILAE 2023 neonatal guideline. The exception is a likely channelopathy (a family history, for example). Then phenytoin or carbamazepine is used. Levetiracetam is second-line and may be the preferred pick with cardiac disease. It is not labeled, so this is specialist use.
  • Pregnancy: Two decades of human and registry data show no higher risk of major birth defects or miscarriage. Animal studies did show developmental toxicity. The AAN/AES/SMFM 2024 guideline says to consider lamotrigine, levetiracetam or oxcarbazepine when appropriate. Give at least 0.4 mg of folic acid daily, before conception and through pregnancy. Levels drop, most of all in the third trimester. Doses may need to rise. Monitoring stays close after delivery too, especially if the dose was changed. In status epilepticus, stopping the seizure comes first. Encourage enrollment in the North American Antiepileptic Drug Pregnancy Registry.
  • Lactation: It passes into breast milk. Effects on the infant are not known. Weigh the benefits of breastfeeding against the mother's need for the drug.
  • Older Adults: clearance runs about 38% lower because renal function drops. Dose by creatinine clearance. Watch for somnolence and falls.
  • Renal Impairment: adult maintenance by CrCl (mL/min/1.73 m²): above 80, 500–1,500 mg every 12 hr; 50–80, 500–1,000 mg every 12 hr; 30–50, 250–750 mg every 12 hr; below 30, 250–500 mg every 12 hr. Dialysis: 500–1,000 mg every 24 hr plus 250–500 mg after each dialysis. The label says nothing about loading doses or CRRT. Dose with pharmacy.
  • Hepatic Impairment: no dose adjustment needed.
  • Obesity / Dosing Weight: The status epilepticus load runs on actual weight, up to the 4,500 mg cap (reached at 75 kg). Adult maintenance doses are not weight-based.

Field & Transport Considerations

  • Scope: This lives in the ED, the ICU and critical-care and flight transport (RN, paramedic and CCT under protocol). Some ground EMS agencies carry it too. What is allowed varies by state and agency protocol.
  • Storage & Stability: Keep vials and tablets at 25°C (77°F). Excursions of 15–30°C (59–86°F) are allowed. Use a diluted dose within 4 hr at room temperature.
  • Carried Concentration: vials hold 100 mg/mL (500 mg/5 mL). A full 4,500 mg load is 45 mL of concentrate (9 vials), and it gets diluted before use. At the label limit of 15 mg/mL that means at least 300 mL (ESETT used 50 mg/mL). Premixed bags hold 500, 1,000 or 1,500 mg, so a large load needs more than one bag. They are labeled for patients 16 yr and older only.
  • Infusions in Transport: Run it on a pump. At handoff, confirm the total dose (mg) and the volume remaining.
  • Airway: 1 in 5 patients in the ESETT levetiracetam arm (20%) needed intubation within 60 min. Have airway equipment ready after the benzodiazepines and a second-line load.
  • Handoff Essentials: seizure onset time; benzodiazepine doses and times; load start and stop times and total mg; current seizure activity and mental status; home antiseizure drugs and last dose.

Clinical Pearls

Exam discriminator: second-line agents (ESETT doses):
  • Levetiracetam 60 mg/kg (max 4,500 mg): least hypotension (0.7%); renally cleared; few drug interactions
  • Fosphenytoin 20 mg PE/kg (max 1,500 mg PE): rate-limited; hypotension and arrhythmia; avoid with AV block
  • Valproate 40 mg/kg (max 3,000 mg): avoid in liver, mitochondrial (POLG) or urea-cycle disease, pregnancy and under 2 yr; hyperammonemia
  • Efficacy: about 47%, 45% and 46% seizure cessation at 60 min
  • Safety did not differ significantly. Still, the only life-threatening arrhythmia (0.7%) and the most deaths (4.7% vs 2.4% fosphenytoin and 1.6% valproate) happened in the levetiracetam arm
The home drug is not a reason to skip the load: Someone already on levetiracetam still gets the same 60 mg/kg IV load. Pick among levetiracetam, fosphenytoin and valproate based on each patient's safety profile. Record the home drug and the last dose at handoff.
Quiet is not the same as stopped: A patient who does not start waking up after the convulsions stop may have nonconvulsive status epilepticus. Refractory status epilepticus is usually nonconvulsive, so it needs continuous EEG.
Name mix-ups: Keppra gets mixed up with Keflex and Kaletra. levETIRAcetam gets mixed up with lamoTRIgine, levOCARNitine and levoFLOXacin. Read back the full generic name and the indication.
Neonates are different: First-line, phenobarbital kept 80% of neonates seizure-free for 24 hr. Levetiracetam kept 28% seizure-free. Phenobarbital stays first-line whatever the cause, cardiac disease included. The exception is a likely channelopathy (a family history, for example). Then phenytoin or carbamazepine is used. Levetiracetam is second-line. With cardiac disease it may be the preferred second-line drug, because phenytoin and lidocaine can cause arrhythmias.
Remember the post-dialysis dose: A 4-hr hemodialysis run removes about half of the drug. Patients on dialysis need a supplemental dose after each session, or breakthrough seizures follow.

Pharmacology

Mechanism of Action

  • Binds synaptic vesicle protein 2A (SV2A), which regulates neurotransmitter release. That means less neuronal hyperexcitability and fewer seizures. The exact mechanism is not fully known.
  • Chemically unrelated to other antiseizure drugs, and it does not block cardiac sodium channels. So there is no rate-related hypotension or conduction block, and no significant QTc prolongation at 5,000 mg.

Pharmacokinetics

RouteOnsetPeakDuration
IV
Seizure stop: median about 10 min in a small ESETT subset (n=14; not a pharmacologic onset)
End of a 15-min infusion
About 12 hr (dosed every 12 hr)
PO (immediate release)
Rapid, almost complete absorption
About 1 hr
About 12 hr (dosed every 12 hr)
  • Half-life: adults 6–8 hr; children about 5 hr; longer in older adults and in renal impairment.
  • Metabolism: not CYP450-dependent; 24% hydrolyzed (acetamide group) to an inactive metabolite.
  • Elimination: The kidneys excrete 66% unchanged. Clearance tracks creatinine clearance.
  • Protein binding / Vd: Less than 10% binds to protein, and volume of distribution sits close to total body water. Oral bioavailability is almost complete, so IV and PO doses match.

Names & Classification

Generic Name
Levetiracetam
Brand Names
Keppra (tablets, oral solution, injection), Keppra XR; generics; premixed levetiracetam in sodium chloride injection
Pharmacologic Class
Pyrrolidone derivative; SV2A ligand
Therapeutic Class
Antiseizure medication (anticonvulsant)
Controlled Substance
Not controlled
ISMP High-Alert
No
Look-Alike / Sound-Alike
Keppra / Keflex; Keppra / Kaletra; levETIRAcetam / lamoTRIgine; levETIRAcetam / levOCARNitine; levETIRAcetam / levoFLOXacin

References

  1. UCB, Inc. (2025). Keppra (levetiracetam) injection, for intravenous use [prescribing information]. DailyMed, National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c6d5784d-abf9-45fe-ac5a-d5c53bd50f7e
  2. Smith, M. D., Sampson, C. S., Wall, S. P., & Diercks, D. B. (American College of Emergency Physicians Clinical Policies Subcommittee on Seizures). (2024). Clinical policy: Critical issues in the management of adult patients presenting to the emergency department with seizures. Annals of Emergency Medicine, 84(1), e1–e12. https://doi.org/10.1016/j.annemergmed.2024.02.018
  3. Kapur, J., Elm, J., Chamberlain, J. M., Barsan, W., et al., for the NETT and PECARN Investigators. (2019). Randomized trial of three anticonvulsant medications for status epilepticus (ESETT; landmark trial). New England Journal of Medicine, 381(22), 2103–2113. https://doi.org/10.1056/NEJMoa1905795
  4. Lyttle, M. D., Rainford, N. E. A., Gamble, C., Messahel, S., et al. (2019). Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): A multicentre, open-label, randomised trial (landmark trial). The Lancet, 393(10186), 2125–2134. https://doi.org/10.1016/S0140-6736(19)30724-X
  5. Dalziel, S. R., Borland, M. L., Furyk, J., Bonisch, M., et al., for the PREDICT research network. (2019). Levetiracetam versus phenytoin for second-line treatment of convulsive status epilepticus in children (ConSEPT): An open-label, multicentre, randomised controlled trial (landmark trial). The Lancet, 393(10186), 2135–2145. https://doi.org/10.1016/S0140-6736(19)30722-6
  6. Pressler, R. M., Abend, N. S., Auvin, S., Boylan, G., et al. (2023). Treatment of seizures in the neonate: Guidelines and consensus-based recommendations. Special report from the ILAE Task Force on Neonatal Seizures. Epilepsia, 64(10), 2550–2570. https://doi.org/10.1111/epi.17745
  7. Sharpe, C., Reiner, G. E., Davis, S. L., Nespeca, M., et al. (2020). Levetiracetam versus phenobarbital for neonatal seizures: A randomized controlled trial (NEOLEV2). Pediatrics, 145(6), e20193182. https://doi.org/10.1542/peds.2019-3182
  8. Rossetti, A. O., Claassen, J., & Gaspard, N. (2024). Status epilepticus in the ICU. Intensive Care Medicine, 50(1), 1–16. https://doi.org/10.1007/s00134-023-07263-w
  9. American Heart Association (2025). 2025 AHA Guidelines for CPR and ECC, Part 11: Post-Cardiac Arrest Care. Circulation, 152(16 suppl 2). Hirsch, K. G., et al. https://cpr.heart.org/en/resuscitation-science/cpr-and-ecc-guidelines/post-cardiac-arrest-care
  10. Pack, A. M., Oskoui, M., Williams Roberson, S., et al. (AAN, AES and SMFM). (2024). Teratogenesis, perinatal, and neurodevelopmental outcomes after in utero exposure to antiseizure medication: Practice guideline. Neurology, 102(11), e209279. https://doi.org/10.1212/WNL.0000000000209279
  11. Glauser, T., Shinnar, S., Gloss, D., Alldredge, B., et al. (2016). Evidence-based guideline: Treatment of convulsive status epilepticus in children and adults: Report of the Guideline Committee of the American Epilepsy Society. Epilepsy Currents, 16(1), 48–61. https://doi.org/10.5698/1535-7597-16.1.48
  12. Institute for Safe Medication Practices (ISMP). (2024). ISMP List of Confused Drug Names. https://www.ismp.org/recommendations/confused-drug-names-list

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