Acetaminophen
Therapeutic: 10-30 μg/mL
Serum acetaminophen (APAP) level is critical for overdose assessment. Use Rumack-Matthew nomogram at 4+ hours post-ingestion to determine need for N-acetylcysteine (NAC).
Learn MorePanel Components
Salicylate
Therapeutic: 10-30 mg/dL
Aspirin toxicity can be life-threatening. Levels guide alkalinization therapy and hemodialysis decisions. Watch for mixed acid-base disturbances and altered mental status.
Learn MoreEthanol Level
Legal limit: 80 mg/dL (0.08%)
Serum ethanol guides clinical picture interpretation. Tolerance varies widely. Consider other causes if mental status doesn't correlate with level.
Learn MoreToxic Alcohols
Methanol/Ethylene Glycol: Undetectable
Methanol and ethylene glycol cause severe toxicity. Check osmol gap, anion gap. Fomepizole is antidote; hemodialysis for severe cases.
Learn MoreUrine Drug Screen
Qualitative: Positive/Negative
Immunoassay-based screens detect drug classes. Know limitations: false positives/negatives common. Synthetic opioids often missed. Confirmation testing may be needed.
Learn MoreDigoxin
Therapeutic: 0.8-2.0 ng/mL
Narrow therapeutic index medication. Toxicity causes life-threatening arrhythmias. Digoxin-Fab antibodies (DigiFab) for severe toxicity. Check potassium!
Learn MoreLithium
Therapeutic: 0.6-1.2 mEq/L
Narrow therapeutic window. Toxicity causes neurologic symptoms. Hemodialysis indicated for severe toxicity. Chronic toxicity can occur at lower levels than acute.
Learn MoreCarbon Monoxide
Non-smoker: <3% | Smoker: <10%
Carboxyhemoglobin (COHb) level confirms CO exposure. High-flow O2 is treatment. Consider hyperbaric oxygen for severe toxicity, pregnancy, or neurologic symptoms.
Learn MoreMedical Disclaimer
- For Educational Purposes Only: This content is intended for educational reference and should not be used for clinical decision-making.
- Not a Substitute for Professional Judgment: Always consult your local protocols, institutional guidelines, and supervising physicians.
- Verify Before Acting: Users are responsible for verifying information through authoritative sources before any clinical application.
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The clinical content and references are curated and reviewed by myself; however, AI was used to assist in organizing, paraphrasing, and formatting the information presented.